biocomma® Frits for Affinity Chromatography (AC) Columns

biocomma ^® affinity chromatography column frit is specially used for affinity chromatography column after using Sepharose 4B as basis, it is widely used to extract restructuring protein, purify antibody or separate from effective constituent.

Hydrophilic Frits

Apply for leading hydrophilic UHWMPE production technology.

biocomma ^® affinity chromatography column frit, hydrophilic frit shall be moistened by water solution.

Hydrophilic frit shall have unique advantages during filtration for water solution.

Left: hydrophilic frit, droplet fast penetrates into frit; right: hydrophobic frit, droplet fails to penetrate into frit, so it must be pressurized.

Special Optimization for Affinity Chromatography Column

Frit shall be positioned at top or bottom of sorbent to prevent leaking from expensive base material.

Special optimization for affinity chromatography column assures flow rate of 1-2ml/m or 1-2droplets/s under gravity method.

Meanwhile, after comparison between such frit and other same kind of product, this shall not absorb protein after introduction to hydrophilic base group. In addition, such hydrophilic base group is hard to create air bubble during operation, herein air bubble shall reduce flow rate and make uneven base material while liquid passes by.

Notice: Flow rate still closely relates with particulate diameter and its evenness for sorbent.

Quality Control

Full traceablity use ERP management system before detailed record for each process of frit production.

 

biocomma ^® Frits for Affinity Chromatography Column Spesc Sheet

Cat.NO.	Diameter（mm）	Thickness(mm)	Pore(μm)	DNA(mL)	Package（Pcs/PK）
ACF058-16-50	5.8	1.6	50	1	1,000
ACF090-16-50	9	1.6	50	3	1,000
ACF091-16-50	9.1	1.6	50	3	1,000
ACF130-16-50	13	1.6	50	6	1,000
ACF158-16-50	15.8	1.6	50	12	1,000
ACF228-16-50	22.8	1.6	50	30	1,000
ACF266-16-50	26.6	1.6	50	60	1,000
ACF495-16-50	49.5	1.6	50	300	1,000
Custom	1-50	1.6/2.5	20/50/80	-	-